ATTRACT

Does ibuprofen increase the risk of myocardial infarction?

Associated Tags: adverse events, ibuprofen, myocardial infarction, NSAID

Question answered: 08/02/10

Is there evidence to support the use of patella tendon graft over hamstring graft for anterior cruciate reconstruction, in young men who engage in football and Rugby?

Associated Tags: graft, hamstring, patella

Question answered: 01/02/10

I have a patient who is 2 weeks postpartum with ankle swelling and high BP. She is currently on 800 mg of labetalol in 3 divided doses. How long can I increase labetalol and what is the maximum dose? When do I need to refer her?

Associated Tags: beta-blockers, hypertension, postpartum

Question answered: 28/01/10

Should lithium be stopped immediately with abnormal thyroid function test? My patient developed hyperthyroidism while on lithium long term.

Associated Tags: hyperthyroid, lithium

Question answered: 22/01/10

Is there any evidence that use of a hypnotic at the start of CPAP for sleep apnoea is beneficial in promoting acceptance of the treatment and if so which hypnotic should be used?

Associated Tags: CPAP, hypnotics, sleep apnoea

Question answered: 21/01/10

Is there any current prevalence data for patients having confirmed swine flu despite immunisation with pandemrix?

Associated Tags: H1N1, pandemrix, swine flu

Question answered: 20/01/10

What is the evidence for outcome in using Fibrates to treat lipidaemia?

Associated Tags: fibrates, hyperlipidaemia

Question answered: 19/01/10

What is the sensitivity and specificity of CRP for infection?

Associated Tags: CRP, infection, sensitivity, senstivity

Question answered: 18/01/10

What has been the causes of death in swine flu e.g. were they respiratory or due to secondary bacterial infection? Also is haemoptysis a feature?

Associated Tags: H1N1, haemoptysis, infectious disease, mortality, respiratory, swine flu

Question answered: 13/01/10

Does terbinafine reduce the efficacy of the COCP (loestrin 20)?

Associated Tags: antifungal, COC, efficacy, interactions, terbinafine

Question answered: 11/01/10

A patient on the cocp has a heavy episode of intermenstrual bleeding - presumed to be a miscarriage, how long is pregnancy test positive after a miscarriage, when does a pregnancy test first become positive and is it worth the patient having a scan if the bleeding settles and pregnancy test is negative then.

Associated Tags: miscarriage

Question answered: 30/12/09

What is the latest evidence for SSRI's in the treatment of pre-menstrual syndrome/premenstrual dysphoric disorder (PMDD)?

Associated Tags: antidepressants, PMDD, premenstrual syndrome, SSRIs

Question answered: 23/12/09

Which of lisinopril 10mg or atorvastatin 40mg is most likely to cause impotence?

Associated Tags: atorvastatin, impotence, lisinopril, sexual dysfunction, statins

Question answered: 17/12/09

Is there any evidence that you must give depo provera in to the gluteus muscle, and that it is ineffectual/ dangerous/ any thing else if given into deltoid?

Associated Tags: gluteal, injection site, contraception, deltoid, depo-provera

Question answered: 07/12/09

Is there any evidence that co-prescribing a proton pump inhibitor with aspirin does actually reduce the Gastro-intestinal side effects of aspirin.

Associated Tags: aspirin, PPI

Question answered: 26/11/09

Is there any evidence for the use of pregabalin in trigeminal neuralgia?

Associated Tags: pregabalin, trigeminal neuralgia

Question answered: 23/11/09

NICE have recently recommended Vitamin D supplement to reduce falls in the elderly. Does this guidance apply only to those in Nursing homes or to an age group? What is the evidence for this intervention? What is the NNT to prevent 1 adverse outcome?

Associated Tags: cost effectiveness, elderly, falls, Musculoskeletal disease, vitamin d

Question answered: 21/11/09

If someone has osteopenia on a DEXA scan when should they have a further DEXA scan to see if there has been any deterioration in bone density? What is the up to date advice on the management of osteopenia?

Associated Tags: DEXA, osteopenia

Question answered: 19/11/09

Is there a systematic review or other good evidence regarding the use of dental appliances in the treatment of sleep apnoea?

Associated Tags: oral appliances, Sleep apnoea

Question answered: 18/11/09

Have there been changes to advice for people with artificial joints - do they still need antibiotic cover pre dental treatment?

Associated Tags: antibiotics, oral health

Question answered: 16/11/09

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